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Ming Lei Selected Research

Matrix Metalloproteinases (MMPs)

1/2018MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells.
4/2014Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.
5/2011Deficiency in TIMP-3 increases cardiac rupture and mortality post-myocardial infarction via EGFR signaling: beneficial effects of cetuximab.

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Ming Lei Research Topics

Disease

62Neoplasms (Cancer)
05/2024 - 02/2004
15Inflammation (Inflammations)
01/2024 - 10/2011
12Hypertrophy
10/2023 - 12/2011
10COVID-19
12/2023 - 01/2020
10Cardiomegaly (Heart Hypertrophy)
03/2021 - 10/2004
9Necrosis
11/2023 - 05/2009
9Alzheimer Disease (Alzheimer's Disease)
10/2023 - 04/2007
9Prostatic Neoplasms (Prostate Cancer)
01/2023 - 05/2010
8Adenocarcinoma
05/2024 - 01/2021
8Sepsis (Septicemia)
01/2022 - 10/2011
7Cardiac Arrhythmias (Arrythmia)
01/2023 - 10/2009
7Heart Failure
01/2022 - 08/2002
6Stomach Neoplasms (Stomach Cancer)
05/2024 - 08/2016
6Heart Diseases (Heart Disease)
12/2023 - 11/2011
6Colorectal Neoplasms (Colorectal Cancer)
01/2023 - 01/2021
6Leukemia
10/2022 - 09/2012
6Hepatocellular Carcinoma (Hepatoma)
04/2022 - 05/2016
6Infections
09/2020 - 03/2010
5Neoplasm Metastasis (Metastasis)
04/2024 - 02/2009
5Acute Lung Injury
01/2024 - 08/2019
5Ventricular Fibrillation
12/2023 - 10/2009
5Polymorphic catecholergic ventricular tachycardia
12/2023 - 03/2011
5Osteoarthritis
03/2023 - 03/2010
5Fibrosis (Cirrhosis)
01/2023 - 06/2011
5Pain (Aches)
08/2022 - 11/2015
5Parkinson Disease (Parkinson's Disease)
01/2022 - 01/2015
5Myocardial Infarction
01/2022 - 10/2009
5Reperfusion Injury
05/2020 - 02/2010
5Carcinogenesis
01/2018 - 02/2012
5Ischemia
01/2015 - 02/2005
5Sick Sinus Syndrome
01/2013 - 09/2005
4Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
12/2023 - 04/2019
4Cognitive Dysfunction
10/2023 - 01/2018
4Atrophy
10/2023 - 10/2008
4Schizophrenia (Dementia Praecox)
10/2021 - 02/2013
4Septic Shock (Toxic Shock Syndrome)
01/2020 - 10/2011
3Lung Injury
01/2024 - 08/2019
3Ventricular Tachycardia
12/2023 - 02/2013
3Insulin Resistance
12/2023 - 01/2023
3Cardiovascular Diseases (Cardiovascular Disease)
12/2023 - 01/2015
3Melanoma (Melanoma, Malignant)
09/2023 - 11/2014
3Multiple Myeloma
11/2022 - 09/2012
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2022 - 01/2007
3Myocardial Ischemia (Ischemic Heart Diseases)
01/2022 - 01/2018
3Disease Progression
01/2022 - 02/2019
3Ischemic Stroke
01/2021 - 01/2015
3Hypertension (High Blood Pressure)
01/2021 - 09/2006

Drug/Important Bio-Agent (IBA)

36Proteins (Proteins, Gene)FDA Link
04/2024 - 11/2004
11NivolumabIBA
05/2024 - 01/2021
10LipopolysaccharidesIBA
01/2024 - 10/2011
10Biomarkers (Surrogate Marker)IBA
08/2022 - 03/2015
9Messenger RNA (mRNA)IBA
04/2024 - 10/2004
9MicroRNAs (MicroRNA)IBA
07/2023 - 05/2010
8Adrenergic Agents (Adrenergic Drugs)IBA
01/2022 - 09/2006
7Fingolimod Hydrochloride (FTY720)FDA Link
01/2018 - 02/2010
6Therapeutic UsesIBA
01/2024 - 01/2013
6Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
12/2023 - 03/2011
6CytokinesIBA
02/2023 - 01/2018
6CalciumIBA
06/2022 - 09/2006
5Long Noncoding RNAIBA
02/2024 - 12/2019
5EnzymesIBA
01/2022 - 11/2012
5triptolideIBA
01/2017 - 01/2012
4Peptides (Polypeptides)IBA
10/2023 - 04/2007
4Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
10/2023 - 11/2020
4Histones (Histone)IBA
10/2022 - 01/2013
4MethyltransferasesIBA
10/2022 - 01/2013
4Carcinoembryonic AntigenIBA
09/2022 - 01/2021
4C-Reactive ProteinIBA
03/2022 - 01/2020
4Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2022 - 12/2011
4DNA (Deoxyribonucleic Acid)IBA
08/2020 - 01/2007
4Voltage-Gated Sodium ChannelsIBA
02/2019 - 01/2007
4p21-Activated KinasesIBA
01/2018 - 09/2010
4sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
07/2015 - 02/2010
3AntioxidantsIBA
04/2024 - 11/2018
3Telomerase (Telomerase Reverse Transcriptase)IBA
02/2024 - 03/2015
3LipidsIBA
09/2023 - 11/2022
3Circular RNAIBA
07/2023 - 01/2020
3LigandsIBA
03/2023 - 01/2020
3human ERBB2 proteinIBA
01/2023 - 01/2021
3Sirtuin 1IBA
01/2023 - 01/2012
3AntigensIBA
01/2023 - 12/2021
3B7-H1 AntigenIBA
01/2022 - 01/2021
3Immune Checkpoint InhibitorsIBA
01/2022 - 01/2021
3IpilimumabIBA
01/2022 - 01/2021
3Atrial Natriuretic Factor (ANF)IBA
03/2021 - 10/2004
3Angiotensin IIIBA
02/2021 - 12/2011
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 03/2009
3Antiviral Agents (Antivirals)IBA
09/2020 - 07/2013
3SteroidsIBA
10/2018 - 01/2013
3SodiumIBA
01/2018 - 01/2007

Therapy/Procedure

31Therapeutics
12/2023 - 08/2005
11Drug Therapy (Chemotherapy)
05/2024 - 01/2012
5Ligation
01/2021 - 10/2004
5Punctures
01/2021 - 04/2007
4Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2024 - 01/2012
4Percutaneous Nephrolithotomy
10/2016 - 04/2007
3Radiotherapy
11/2023 - 01/2021
3Immunotherapy
04/2023 - 06/2021
3Stents
04/2022 - 08/2007
3Length of Stay
01/2022 - 06/2014